TBNK Mimic™ (formerly TruCytes® Lymphocyte Subsets Control) is a lyophilized cell mimic designed for reliable performance checks and normalization controls in immunophenotyping and flow cytometry workflows. These controls feature T cell, B cell and NK cell markers with scatter characteristics that closely resemble lymphocyte, monocyte and granulocyte populations. Each control includes well‑defined populations that reflect physiologically relevant antigen densities: CD4+ T cells (CD45+, CD3+, CD4+), CD8+ T cells (CD45+, CD3+, CD8+), B cells (CD45+, CD3−, CD19+), NK cells (CD45+, CD3−, CD16/56+), classical monocytes (CD45+, CD14+) and granulocytes (CD45+). Their engineered FSC and SSC profiles closely resemble the scatter characteristics of human peripheral blood populations, enabling confident population discrimination and gating across diverse cytometry platforms.
Offering superior lot‑to‑lot reproducibility and exceptional long‑term stability, TBNK Mimics outperform fresh primary cells, frozen preparations and conventional lyophilized products. With no biohazard material and no special handling or disposal requirements, they provide a dependable alternative to biologically derived controls while maintaining consistent antigen presentation and physiologically relevant scatter characteristics. This combination of stability, reproducibility and well‑defined population structure supports accurate gating, antibody performance assessment and instrument verification across daily QC, assay validation and longitudinal performance monitoring. The lyophilized format ensures consistent reconstitution and extended shelf life, making TBNK Mimics suitable for multi‑site standardization, training and long‑term assay harmonization.
TBNK Mimic™
TBNK Mimic™
Specifications
| Specification | Value |
|---|---|
| Format | Lyophilized cell mimic; six defined populations with lymphocyte, monocyte and granulocyte scatter characteristics |
| Available Sizes | 1 kit (SSB-31-A) |
| Cell Populations | CD4+ T cells (CD45+, CD3+, CD4+), CD8+ T cells (CD45+, CD3+, CD8+), B cells (CD45+, CD3−, CD19+), NK cells (CD45+, CD3−, CD16/56+), classical monocytes (CD45+, CD14+), granulocytes (CD45+, CD16+) |
| Biomarkers | CD45, CD3, CD4, CD8, CD19, CD16/56, CD14 |
| Scatter Characteristics | Engineered FSC and SSC profiles closely resembling human peripheral blood populations |
| Application | Immunophenotyping QC, TBNK panel verification, antibody performance assessment, instrument standardization, multi-site harmonization, and flow cytometry training |
| Instrument Compatibility | Compatible across diverse cytometry platforms; supports multi-site standardization |
| Handling & Safety | No biohazardous material; no special handling or disposal required |
| Storage Temp | -20°C |
| Shipping Temp | No Ice |
| Shelf Life | 36 months |
| Guaranteed Expiration Date | >6 months at shipping |
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Questions
TBNK Mimic™ is a lyophilized, polymer-based cell mimic used as a standardized reference control for T-, B- and NK-cell immunophenotyping by flow cytometry. It provides defined cell-like populations, stable biomarker expression and biologically relevant scatter to support assay development, validation and routine performance monitoring.
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