TBNK Mimic™ (formally known as TruCytes LymphoCytes Subsets) is a lyophilized cell mimic designed for reliable performance checks and normalization controls in immunophenotyping and flow cytometry workflows. These controls feature T cell, B cell and NK cell markers with scatter characteristics that closely resemble lymphocyte, monocyte and granulocyte populations. Each control includes well‑defined populations that reflect physiologically relevant antigen densities: CD4+ T cells (CD45+, CD3+, CD4+), CD8+ T cells (CD45+, CD3+, CD8+), B cells (CD45+, CD3−, CD19+), NK cells (CD45+, CD3−, CD16/56+), classical monocytes (CD45+, CD14+) and granulocytes (CD45+). Their engineered FSC and SSC profiles closely resemble the scatter characteristics of human peripheral blood populations, enabling confident population discrimination and gating across diverse cytometry platforms.

Offering superior lot‑to‑lot reproducibility and exceptional long‑term stability, TBNK Mimics outperform fresh primary cells, frozen preparations and conventional lyophilized products. With no biohazard material and no special handling or disposal requirements, they provide a dependable alternative to biologically derived controls while maintaining consistent antigen presentation and physiologically relevant scatter characteristics. This combination of stability, reproducibility and well‑defined population structure supports accurate gating, antibody performance assessment and instrument verification across daily QC, assay validation and longitudinal performance monitoring. The lyophilized format ensures consistent reconstitution and extended shelf life, making TBNK Mimics suitable for multi‑site standardization, training and long‑term assay harmonization.